Two sample MR report
WBSCR27_Monocyte (Mono) against finn-b-ASTHMA_ALLERG_EXMORE
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 5 | 0.0201859 | 0.0795245 | 0.8160273 |
| Weighted median | 5 | 0.0666581 | 0.0200401 | 0.0008803 |
| Inverse variance weighted | 5 | 0.0640123 | 0.0150935 | 0.0000222 |
| Simple mode | 5 | 0.0667308 | 0.0253962 | 0.0583333 |
| Weighted mode | 5 | 0.0667874 | 0.0251994 | 0.0569603 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 0.0079204 | 3 | 0.9998130 |
| Inverse variance weighted | 0.3229866 | 4 | 0.9882824 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| 0.0478427 | 0.0852344 | 0.6137866 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 5.58e-05 | 0 | TRUE | 0.4830266 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
